Sensitive, Efficient and Portable Analysis of Molecular Exchange Processes by Hyperpolarized Ultrafast NMR

Yashu Kharbanda, Mateusz Urbańczyk, Vladimir V. Zhivonitko, Sarah Mailhiot, Mikko I. Kettunen, Ville-Veikko Telkki

A hyperpolarized ultrafast diffusion exchange spectroscopy method is introduced, which allows highly sensitive and efficient quantification of molecular exchange rates by using low-cost, low-field, single-sided and portable NMR instruments. The method can be used to investigate exchange processes in many fields ranging from intra-extracellular exchange of metabolites to atmospheric surfactant solutions.